Article
Predictive genomic and transcriptomic analysis on endoscopic ultrasound-guided fine needle aspiration materials from primary pancreatic adenocarcinoma: a prospective multicentre study.
EBioMedicine - 1 Nov 2024
Nicolle Rémy, Canivet Cindy, Palazzo Laurent, Napoléon Bertrand, Ayadi Mira, Pignolet Camille, Cros Jérôme, Gourgou Sophie, Selves Janick, Torrisani Jérôme, Dusetti Nelson, Cordelier Pierre, Buscail Louis, Bournet Barbara
Abstract excerpt
BACKGROUND: We apply endoscopic ultrasound-guided fine needle aspiration biopsy to cytopathologically diagnose and sample nucleic acids from primary tumours regardless of the disease stage. METHODS: 397 patients with proven pancreatic adenocarcinoma were included and followed up in a multicentre prospective study. DNA and mRNA were extracted from materials of primary tumours obtained by endoscopic...
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