Article
Impact of Smad4 and p53 mutations on the prognosis of patients with pancreatic ductal adenocarcinoma undergoing chemotherapy.
International journal of clinical oncology - 1 Nov 2023
Kamata Ken, Takenaka Mamoru, Nishida Naoshi, Hara Akane, Otsuka Yasuo, Tanaka Hidekazu, Omoto Shunsuke, Minaga Kosuke, Yamao Kentaro, Chiba Yasutaka, Sakai Kazuko, Nishio Kazuto, Watanabe Tomohiro, Kudo Masatoshi
Abstract excerpt
BACKGROUND: This prospective cohort study evaluated the feasibility of using endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) samples for comprehensive mutational analysis of cancer-related genes using microtissues. METHODS: Fifty patients with suspected pancreatic cancer presenting consecutively at the Kindai University Hospital between January 2018 and January 2019 were enrolled. Cancerous tissues from...
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