Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Does ACE2 mediate the detrimental effect of exposures related to COVID-19 risk: A Mendelian randomization investigation.

Journal of medical virology - 1 Jan 2023

Au Yeung Shiu Lun, Wong Tommy Hon Ting, He Baoting, Luo Shan, Kwok Kin On

Abstract excerpt

OBJECTIVES: Adiposity, smoking, and lower socioeconomic position (SEP) increase COVID-19 risk while the association of vitamin D, blood pressure, and glycemic traits in COVID-19 risk were less clear. Whether angiotensin-converting enzyme 2 (ACE2), the key receptor for SARS-CoV-2, mediates these associations has not been investigated. We conducted a Mendelian randomization study to assess the role of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme 2
Share to COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Obesity

Share to SARS-CoV-2

Share to Smoking

Share to Vitamin D

Source

Open in PubMed Open full text

Identifiers

PMID: 36217700
DOI: 10.1002/jmv.28205
PMCID: PMC9874514

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Does ACE2 mediate the detrimental effect of exposures related to COVID-19 risk: A Mendelian randomization investigation.PMID 36217700Read ↗

Cardiometabolic Risk Factors for COVID-19 Susceptibility and Severity: A Mendelian Randomization AnalysisSemantic proximity Read ↗

Cardiometabolic risk factors for COVID-19 susceptibility and severity: A Mendelian randomization analysis.Semantic proximity Read ↗

Unravel the distinct effects of adiposity at different life stages on COVID-19 susceptibility and severity: A life-course Mendelian randomization study.Semantic proximity Read ↗

Genetically Predicted Higher Educational Attainment Decreases the Risk of COVID-19 Susceptibility and Severity: A Mendelian Randomization Study.Semantic proximity Read ↗

Causal associations and shared genetics between hypertension and COVID-19.Semantic proximity Read ↗

The relationship between BMI and COVID-19: exploring misclassification and selection bias in a two-sample Mendelian randomisation studySemantic proximity Read ↗

Estimating causal effects of atherogenic lipid-related traits on COVID-19 susceptibility and severity using a two-sample Mendelian randomization approach.Semantic proximity Read ↗

Shared genomic architecture between COVID-19 severity and numerous clinical and physiologic parameters revealed by LD score regression analysis.Semantic proximity Read ↗

Identifying factors contributing to increased susceptibility to COVID-19 risk: a systematic review of Mendelian randomization studies.Semantic proximity Read ↗

ACE2 polymorphisms as potential players in COVID-19 outcomeSemantic proximity Read ↗

Impact of body composition on COVID-19 susceptibility and severity: a two-sample multivariable Mendelian randomization studySemantic proximity Read ↗

ACE2 polymorphisms as potential players in COVID-19 outcome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.