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Article

Telomere Attrition and Clonal Hematopoiesis of Indeterminate Potential in Cardiovascular Disease.

International journal of molecular sciences - 13 Sept 2021

Huang Yi-Chun, Wang Chao-Yung

Abstract excerpt

Clinical evidence suggests that conventional cardiovascular disease (CVD) risk factors cannot explain all CVD incidences. Recent studies have shown that telomere attrition, clonal hematopoiesis of indeterminate potential (CHIP), and atherosclerosis (telomere-CHIP-atherosclerosis, TCA) evolve to play a crucial role in CVD. Telomere dynamics and telomerase have an important relationship with age-related CVD....

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Identifiers

PMID: 34576030
DOI: 10.3390/ijms22189867
PMCID: PMC8467562

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