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Article

Associations of NR5A2 gene polymorphisms with the clinicopathological characteristics and survival of gastric cancer.

International journal of molecular sciences - 10 Dec 2014

Zhang Xunlei, Gu Dongying, Du Mulong, Wang Meilin, Cao Chunxiang, Shen Lili, Kuang Meng, Tan Yongfei, Huo Xinying, Gong Weida, Xu Zhi, Chen Jinfei, Zhang Zhengdong, Tang Cuiju

Abstract excerpt

The orphan nuclear receptor (NR5A2), which belongs to the NR5A subfamily of nuclear receptors, is expressed in developing and adult tissues of endodermal origin, and can contribute to the development of several cancers through regulating cell proliferation. NR5A2 (rs3790843 and rs3790844) single nucleotide polymorphisms (SNPs) genotyping were examined in DNA samples, extracted from paraffin-embedded cancer...

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PMID: 25514243
DOI: 10.3390/ijms151222902
PMCID: PMC4284745

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