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Longitudinal association of peripheral blood DNA methylation with liver fat content: distinguishing between predictors and biomarkers

27 Sept 2024

Abstract excerpt

BACKGROUND: Alterations in DNA methylation (DNAm) have been observed in patients with fatty liver, but whether they are cause or consequence remains unknown. The study aimed to investigate longitudinal association of epigenome-wide DNAm with liver fat content (LFC) in Chinese participants, and explore their temporal relationships. METHODS: Data were obtained from 2 waves over a four-year time period of the...

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PMID: 39334355
DOI: 10.1186/s12944-024-02304-9

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