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Article

Body composition in recurrent prostate cancer and the role of steroidogenic genotype.

Endocrine-related cancer - 1 Dec 2024

Venkatesh Neha, Tidwell Rebecca S, Yu Yao, Aparicio Ana, Zurita Amado J, Subudhi Sumit K, Siddiqui Bilal A, Mukhida Sagar S, Gregg Justin R, Corn Paul G, Koutroumpakis Efstratios, McQuade Jennifer L, Frigo Daniel E, Pilie Patrick G, Huff Chad, Logothetis Christopher J, Hahn Andrew W

Abstract excerpt

Hormone therapy (HT) to treat prostate cancer is reported to cause adverse changes in body composition. Clinically, interpatient body composition changes are heterogeneous, but the biological and clinical determinants of body composition toxicity are unknown. Herein, we test the hypothesis that inherited polymorphisms in steroidogenic genes are associated with differential changes in body composition after HT....

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Share to 3-Oxo-5-alpha-Steroid 4-Dehydrogenase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Membrane Proteins

Share to Neoplasm Recurrence, Local

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Source

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Identifiers

PMID: 39324992
DOI: 10.1530/ERC-24-0195
PMCID: PMC12136150

Genes

BCR
SRD5A2
HSD3B1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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