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In silico design of Mycobacterium tuberculosis multi-epitope adhesin protein vaccines

1 Sept 2024

Abstract excerpt

(Mtb) adhesin proteins are promising candidates for subunit vaccine design. Multi-epitope Mtb vaccine and diagnostic candidates were designed using immunoinformatic tools. The antigenic potential of 26 adhesin proteins were determined using VaxiJen 2.0. The truncated heat shock protein 70 (tnHSP70), 19 kDa antigen lipoprotein (lpqH), Mtb curli pili (MTP), and Phosphate transport protein S1 (PstS1) were selected...

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PMID: 39323805
DOI: 10.1016/j.heliyon.2024.e37536

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