H5N1 clade 2.3.4.4b dynamics in experimentally infected calves and cows.

doi:10.1038/s41586-024-08063-y

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Article

H5N1 clade 2.3.4.4b dynamics in experimentally infected calves and cows.

Nature - 1 Jan 2025

Halwe Nico Joel, Cool Konner, Breithaupt Angele, Schön Jacob, Trujillo Jessie D, Nooruzzaman Mohammed, Kwon Taeyong, Ahrens Ann Kathrin, Britzke Tobias, McDowell Chester D, Piesche Ronja, Singh Gagandeep, Pinho Dos Reis Vinicius, Kafle Sujan, Pohlmann Anne, Gaudreault Natasha N, Corleis Björn, Ferreyra Franco Matias, Carossino Mariano, Balasuriya Udeni B R, Hensley Lisa, Morozov Igor, Covaleda Lina M, Diel Diego G, Ulrich Lorenz, Hoffmann Donata, Beer Martin, Richt Juergen A

Abstract excerpt

In March 2024, highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b H5N1 infections were reported in dairy cows in Texas, USA1. Rapid dissemination to more than 380 farms in 14 states followed2. Here we provide results of two independent clade 2.3.4.4b experimental infection studies evaluating the oronasal susceptibility to and transmission of a US H5N1 bovine isolate, genotype B3.13 (H5N1 B3.13), in...

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PMID: 39321846
DOI: 10.1038/s41586-024-08063-y
PMCID: PMC11754106

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