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Article

Protocol to detect spatio-molecular profiles underlying neuroimaging features in the human cerebellum.

STAR protocols - 20 Dec 2024

Wang Yaping, Wang Kaikai, Madsen Kristoffer Hougaard, Chu Congying, Fan Lingzhong

Abstract excerpt

Imaging transcriptomics offers opportunities to uncover the genetic profiles underlying brain imaging-derived phenotypes (IDPs) but lacks explanation from gene to IDPs. Here, we present a protocol for combining imaging transcriptomics with gene set variation analysis (GSVA) to detect spatio-molecular profiles underlying IDPs in the human cerebellum. We describe the steps for data preparation, model training,...

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Identifiers

PMID: 39316504
DOI: 10.1016/j.xpro.2024.103311
PMCID: PMC11462228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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