Article
Sex-Stratified Genome-Wide Association Study in the Spanish Population Identifies a Novel Locus for Lacunar Stroke.
Stroke - 1 Oct 2024
Cárcel-Márquez Jara, Muiño Elena, Gallego-Fabrega Cristina, Cullell Natalia, Lledós Miquel, Llucià-Carol Laia, Martín-Campos Jesús M, Sobrino Tomás, Campos Francisco, Castillo José, Freijo Marimar, Arenillas Juan Francisco, Obach Victor, Álvarez-Sabín José, Molina Carlos A, Ribó Marc, Jiménez-Conde Jordi, Roquer Jaume, Muñoz-Narbona Lucia, Lopez-Cancio Elena, Millán Mònica, Diaz-Navarro Rosa, Vives-Bauza Cristòfol, Serrano-Heras Gemma, Segura Tomás, Ibañez Laura, Heitsch Laura, Delgado Pilar, Dhar Rajat, Krupinski Jerzy, Prats-Sánchez Luis, Camps-Renom Pol, Guasch Marina, Ezcurra Garbiñe, Blay Natalia, Sumoy Lauro, de Cid Rafael, Montaner Joan, Cruchaga Carlos, Lee Jin-Moo, Martí-Fàbregas Joan, Férnandez-Cadenas Israel
Abstract excerpt
BACKGROUND: Ischemic stroke (IS) represents a significant health burden globally, necessitating a better understanding of its genetic underpinnings to improve prevention and treatment strategies. Despite advances in IS genetics, studies focusing on the Spanish population and sex-stratified analyses are lacking. METHODS: A case-control genome-wide association study was conducted with 9081 individuals (3493 IS...
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