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The repertoire of G-protein-coupled receptor variations in the Japanese population 54KJPN.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Nov 2024

Ikuta Tatsuya, Suzuki Riko, Inoue Asuka

Abstract excerpt

G-protein-coupled receptors (GPCRs) are the largest superfamily in the human genome and the major targets for the market drugs. Recent massive genomics studies revealed numerous natural variations in the general population. 54KJPN is the most extensive Japanese population genomics study, curating the whole genome sequences from about 54,000 individuals. Here, by analyzing 390 non-olfactory GPCR genes in the...

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PMID: 39308264
DOI: 10.1111/gtc.13164

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