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Article

GNAS, not a Highly Mutated Gene, Has Prognostic Significance and Carcinogenic Effects in Osteosarcoma.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 15 Sept 2024

Qi Jin, Huang Yanjiao, Bian Yaogang

Abstract excerpt

BACKGROUND/AIMS: Osteosarcoma is a prevalent and aggressive primary malignant bone tumor affecting children and adolescents. Despite advancements in sequencing technologies, there remains a lack of reliable prognostic biomarkers and effective targeted therapies for osteosarcoma. This study focuses on identifying key prognostic genes, particularly the role of GNAS, in osteosarcoma progression. METHODS:...

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PMID: 39305132
DOI: 10.33594/000000728

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