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Identification of co-expression modules and pathways correlated with osteosarcoma and its metastasis

8 Mar 2019

Abstract excerpt

BACKGROUND: Osteosarcoma is the most common bone tumor that occurs in children. METHODS: To identify co-expression modules and pathways correlated with osteosarcoma and its clinical characteristics, we performed weighted gene co-expression network analysis (WGCNA) on RNA-seq data of osteosarcoma with 52 samples. Then we performed pathway enrichment analysis on genes from significant modules. RESULTS: A total of...

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PMID: 30849987
DOI: 10.1186/s12957-019-1587-7

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