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YAP ‐ TEAD inhibition is associated with upregulation of an androgen receptor mediated transcription program providing therapeutic escape

19 Sept 2024

Abstract excerpt

Cholangiocarcinoma (CCA) is a highly aggressive form of liver cancer and is an increasing cause of cancer-related death worldwide. Despite its increasing incidence globally and alarming mortality, treatment options for CCA have largely remained unchanged, stressing the importance of developing new effective therapies. YAP activation is common in CCA, and its major transcriptional signaling partners are the TEAD...

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Share to Cancer-related gene regulation
Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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PMID: 39300603
DOI: 10.1002/2211-5463.13901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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