Article
Senescent CD4+ T-Cell Phenotypes and Inflammatory Milieu in the Coronary and Systemic Circulation in ST-Elevation Myocardial Infarction: An Exploratory Study.
Journal of vascular research - 1 Jan 2024
Bocanegra-Zamora Fernanda, Espinosa-Bautista Fernanda, Jiménez-Rodríguez Gian M, Masso Felipe, Paez Araceli, Gonzalez-Pacheco Hector, Patlán Mariana, Eid-Lidt Guering, Amezcua-Guerra Luis M
Abstract excerpt
INTRODUCTION: In ST-elevation myocardial infarction (STEMI), inflammation is pivotal, with early senescent CD4+CD28null cells implicated in its pathogenesis. However, the functional phenotype of these cells within the coronary circulation remains unclear. METHODS: We examined CD4+ cell subpopulations in blood samples from the coronary sinus and vena cava of 24 STEMI patients and the cephalic vein of seven healthy...
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