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Inhibition of ADAM17 increases the cytotoxic effect of cisplatin in cervical spheroids and organoids

2 Sept 2024

Abstract excerpt

Introduction: Cervical cancer represents one of the main causes of female, cancer-related mortality worldwide. The majority of cancers are caused by human papillomaviruses such as HPV16 and HPV18. As chemotherapeutic resistance to first-line platinum treatment is still a predominant clinical challenge in advanced cervical cancer, novel treatment options including combinatorial therapies are urgently required to...

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PMID: 39286024
DOI: 10.3389/fonc.2024.1432239

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