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Prognostic Value of IGFBP6 in Breast Cancer: Focus on Glucometabolism

1 Jan 2024

Abstract excerpt

IGFBP6, a member of the IGF binding protein (IGFBP) family, is a specific inhibitor of insulin-like growth factor II (IGF-II) and can inhibit the growth of malignant tumors overexpressing IGF-II. Type 2 diabetes (T2D) is a basic disorder of glucose metabolism that can be regulated by IGF-related pathways. We performed bioinformatics analysis of the TCGA database to explore the possible mechanism of IGFBP6 in...

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PMID: 39275851
DOI: 10.1177/15330338241271998

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