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Characterizing the Mutational Landscape of Diffuse Large B-Cell Lymphoma in a Prospective Cohort of Mexican Patients.

International journal of molecular sciences - 28 Aug 2024

Candelaria Myrna, Cerrato-Izaguirre Dennis, Gutierrez Olga, Diaz-Chavez Jose, Aviles Alejandro, Dueñas-Gonzalez Alfonso, Malpica Luis

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is the most common B-cell malignancy worldwide. Molecular classifications have tried to improve cure rates. We prospectively examined and correlated the mutational landscape with the clinical features and outcomes of 185 Mexican patients (median age 59.3 years, 50% women) with newly diagnosed DLBCL. A customized panel of 79 genes was designed, based on previous international...

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CREB-Binding Protein
DNA-Binding Proteins
Enhancer of Zeste Homolog 2 Protein
Lymphoma, Large B-Cell, Diffuse
Mexico

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Proteins

Receptor, Notch1

Tumor Suppressor Protein p53

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PMID: 39273276
DOI: 10.3390/ijms25179328
PMCID: PMC11394969

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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