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Evaluation of the MHSeqTyper47 kit for forensically challenging DNA samples.

Forensic science international. Genetics - 1 Nov 2022

Feng Yao-Sen, Zhang Chi, Chen Qing-Feng, Wang Yu, Kang Ke-Lai, Zhao Jie, Ji An-Quan, Ye Jian, Wang Le

Abstract excerpt

Microhaplotypes have been highly regarded for forensic mixture DNA deconvolution because they do not experience interference from stutters in the same way as short tandem repeat markers, and they tend to be more polymorphic than single nucleotide polymorphism markers. However, forensic microhaplotype kits have not been reported. The MHSeqTyper47 kit genotypes 47 microhaplotype loci. In this study, MiSeq FGx...

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PMID: 35939876
DOI: 10.1016/j.fsigen.2022.102763

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