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Diversity of Chagas disease diagnostic antigens: Successes and limitations

1 Oct 2024

Abstract excerpt

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, remains a public health issue in endemic regions of the Americas, and is becoming globalised due to migration. In the chronic phase, 2 accordant serological tests are required for diagnosis. In addition to "in-house" assays, commercial tests are available (principally ELISA and rapid diagnostic tests). Herein, we discuss the discovery era of...

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PMID: 39352878
DOI: 10.1371/journal.pntd.0012512

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