Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole exome sequencing analysis of 167 men with primary infertility

12 Sept 2024

Abstract excerpt

BACKGROUND: Spermatogenic failure is one of the leading causes of male infertility and its genetic etiology has not yet been fully understood. METHODS: The study screened a cohort of patients (n = 167) with primary male infertility in contrast to 210 normally fertile men using whole exome sequencing (WES). The expression analysis of the candidate genes based on public single cell sequencing data was performed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Genomic variations and chromosomal abnormalities
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39267058
DOI: 10.1186/s12920-024-02005-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole exome sequencing analysis of 167 men with primary infertilityPMID 39267058Read ↗

Toward clinical exomes in diagnostics and management of male infertility.Semantic proximity Read ↗

Whole-genome sequencing identifies new candidate genes for nonobstructive azoospermia.Semantic proximity Read ↗

Utility of exome sequencing in primary spermatogenic disorders: From research to diagnosticsSemantic proximity Read ↗

Whole-exome sequencing of a large Chinese azoospermia and severe oligospermia cohort identifies novel infertility causative variants and genes.Semantic proximity Read ↗

Point-of-care whole-exome sequencing of idiopathic male infertility.Semantic proximity Read ↗

How exome sequencing improves the diagnostics and management of men with non‐syndromic infertilitySemantic proximity Read ↗

Exome sequencing and functional analyses revealedCETN1variants leads to impaired cell division and male fertilitySemantic proximity Read ↗

Male Infertility Diagnosis: Improvement of Genetic Analysis Performance by the Introduction of Pre-Diagnostic Genes in a Next-Generation Sequencing Custom-Made Panel.Semantic proximity Read ↗

The genetic insights of sporadic male infertility: a systematic review of WES and WGS studies (2014-2024).Semantic proximity Read ↗

Development of a novel next-generation sequencing panel for diagnosis of quantitative spermatogenic impairment.Semantic proximity Read ↗

Transcriptomic signatures for human male infertilitySemantic proximity Read ↗

Sequence analysis of 37 candidate genes for male infertility: challenges in variant assessment and validating genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.