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Exome sequencing and functional analyses revealedCETN1variants leads to impaired cell division and male fertility

1 Sept 2022

Abstract excerpt

Human spermatogenesis requires an orchestrated expression of numerous genes in various germ cell subtypes. Therefore, the genetic landscape of male infertility is highly complex. Known genetic factors alone account for at least 15% of male infertility. However, ~40% of infertile men remain undiagnosed and are classified as idiopathic infertile men. We performed exome sequencing in 47 idiopathic infertile men...

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Share to Epigenetics and DNA Methylation
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36048845
DOI: 10.1093/hmg/ddac216

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