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Article

Five latent factors underlie response to immunotherapy.

Nature genetics - 1 Oct 2024

Usset Joseph, Rosendahl Huber Axel, Andrianova Maria A, Batlle Eduard, Carles Joan, Cuppen Edwin, Elez Elena, Felip Enriqueta, Gómez-Rey Marina, Lo Giacco Deborah, Martinez-Jimenez Francisco, Muñoz-Couselo Eva, Siu Lillian L, Tabernero Josep, Vivancos Ana, Muiños Ferran, Gonzalez-Perez Abel, Lopez-Bigas Nuria

Abstract excerpt

Only a subset of patients treated with immune checkpoint inhibitors (CPIs) respond to the treatment, and distinguishing responders from non-responders is a major challenge. Many proposed biomarkers of CPI response and survival probably represent alternative measurements of the same aspects of the tumor, its microenvironment or the host. Thus, we currently ignore how many truly independent biomarkers there are....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39266764
DOI: 10.1038/s41588-024-01899-0
PMCID: PMC11525176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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