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Establishment and validation of circulating cell-free DNA signatures for nasopharyngeal carcinoma detection

11 Sept 2024

Abstract excerpt

BACKGROUND: Early detection of nasopharyngeal carcinoma (NPC) poses a significant challenge. The absence of highly sensitive and specific diagnostic biomarkers for nasopharyngeal carcinoma contributes to the unfavourable prognosis of NPC patients. Here, we aimed to establish a non-invasive approach for detecting NPC using circulating cell-free DNA (cfDNA). METHODS: We investigated the potential of next-generation...

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PMID: 39265506
DOI: 10.1016/j.ebiom.2024.105321

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