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Article

MicroRNA-15a/16-1 cluster located at chromosome 13q14 is down-regulated but displays different expression pattern and prognostic significance in multiple myeloma.

Oncotarget - 10 Nov 2015

Li Fei, Xu Yan, Deng Shuhui, Li Zengjun, Zou Dehui, Yi Shuhua, Sui Weiwei, Hao Mu, Qiu Lugui

Abstract excerpt

MiRNA-15a/16-1 cluster located at chromosome 13q14 has been confirmed to regulate critical genes associated with cell proliferation, apoptosis and drug resistance in multiple myeloma (MM). However, little is known about their expression pattern and prognostic value in MM patients. In this study, we have analyzed the expression levels of miR-15a/16-1 in 117 MM patients (90 newly diagnosed, 11 relapsed and 16...

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Identifiers

PMID: 26516702
DOI: 10.18632/oncotarget.5681
PMCID: PMC4741998

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