Article
The polymorphism analysis and therapy vaccine target epitopes screening of HPV-35 E6 E7 among the threaten α-9 HPV in Sichuan area.
Virology journal - 9 Sept 2024
He Jiaoyu, Li Tianjun, Cheng Chunlan, Li Ning, Gao Peng, Lei Dan, Liang Rong, Ding Xianping
Abstract excerpt
High-risk human papilloma virus (HR-HPV) persistent infection is closely associated with the development of cervical cancer and squamous intraepithelial lesion (SIL).The α-9 HPVs, which is predominantly composed of HR-HPV types, account for 75% of HR-HPV infection in Sichuan. The oncoproteins E6 and E7 of HPV play a crucial role in tumor initiation and progression. Notably, HPV-35 is the only HR-HPV type within...
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