Article
Causal inference of the effect of plasma proteins on the incidence of oral cancer: two-sample Mendelian randomization.
BMC oral health - 8 Sept 2024
Tian Tao, Li Simin, Hu Shaonan, Zhao Yiwei, Schmalz Gerhard, Acharya Aneesha, Huang Shaohong
Abstract excerpt
OBJECTIVE: This study is aimed to investigate the causal relationship between plasma proteins and oral cancer risk using two-sample MR (Mendelian randomization). METHODS: Summary-level GWAS (genome-wide association study) data on plasma protein levels (4,907 proteins) and oral cancer (6,034 cases, 6,585 controls) of European ancestry were utilized. SNPs (single nucleotide polymorphisms) associated with proteins...
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