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The role of bacterial size, shape and surface in macrophage engulfment of uropathogenic E. coli cells

6 Sept 2024

Abstract excerpt

Uropathogenic Escherichia coli (UPEC) can undergo extensive filamentation in the host during acute urinary tract infections (UTIs). It has been hypothesised that this morphological plasticity allows bacteria to avoid host immune responses such as macrophage engulfment. However, it is still unclear what properties of filaments are important in macrophage-bacteria interactions. The aim of this work was to...

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PMID: 39241059
DOI: 10.1371/journal.ppat.1012458

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