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Article

NSUN2 is critical for mouse oocyte meiosis and early embryonic development.

Reproduction (Cambridge, England) - 1 Dec 2024

Xu Tengteng, Gao Min, Zhang Ling, Cao Tianqi, Qiu Yanling, Liu Simiao, Wu Wenlian, Zhou Yitong, Liu Haiying, Zhang Rui, Ruan Xiaohong, Huang Junjiu

Abstract excerpt

In brief: The mechanism by which the NSUN2 mutation causes female infertility is still unclear. This study reveals the role and potential mechanism of NSUN2 in mouse oocyte maturation and early embryonic development, and provides a resource for elucidating female infertility with NSUN2 mutations. Abstract: Biallelic variants in the NSUN2 gene cause a rare intellectual disability and female infertility in humans....

Read the complete abstract on PubMed

Topics

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Share to Embryonic Development
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39231094
DOI: 10.1530/REP-24-0235

Genes

NSUN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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