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A Decrease in Autophagy Increases the Level of Collagen Type I Expression in Scleral Fibroblasts

4 Sept 2024

Abstract excerpt

PURPOSE: Autophagy dysregulation triggers extracellular matrix remodeling via changes in cellular collagen levels and protease secretion. However, the effect of autophagy on scleral extracellular matrix remodeling in the context of myopia is not fully understood. In this study, we measured the level of autophagy in sclera of form deprivation myopic guinea pigs; we also sought a correlation between the level of...

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PMID: 39229688
DOI: 10.1080/02713683.2024.2393370

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