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Characterization of the role of autophagy in retinal ganglion cell survival over time using a rat model of chronic ocular hypertension

11 Mar 2021

Abstract excerpt

Autophagy is an essential cellular process for the degradation and recycling of cellular components, and its dysregulation has been linked to neuronal cell death and neurodegeneration. In glaucoma, the role of autophagy in retinal ganglion cell (RGC) survival remains contradictory. Moreover, the effects of autophagy modulation at different time-points on RGC survival in a glaucoma model have not been...

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PMID: 33707562
DOI: 10.1038/s41598-021-85181-x

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