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Article

Segregation GWAS to linearize a non-additive locus with incomplete penetrance: an example of horn status in sheep.

Genetics, selection, evolution : GSE - 3 Sept 2024

Duijvesteijn Naomi, van der Werf Julius H J, Kinghorn Brian P

Abstract excerpt

BACKGROUND: The objective of this study was to introduce a genome-wide association study (GWAS) in conjunction with segregation analysis on monogenic categorical traits. Genotype probabilities calculated from phenotypes, mode of inheritance and pedigree information, are expressed as the expected allele count (EAC) (range 0 to 2), and are inherited additively, by definition, unlike the original phenotypes, which...

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Alleles
Genome-Wide Association Study
Horns
Models, Genetic
Pedigree

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39227755
DOI: 10.1186/s12711-024-00928-0
PMCID: PMC11373182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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