Article
Dissection of additive, dominance, and imprinting effects for production and reproduction traits in Holstein cattle.
BMC genomics - 30 May 2017
Jiang Jicai, Shen Botong, O'Connell Jeffrey R, VanRaden Paul M, Cole John B, Ma Li
Abstract excerpt
BACKGROUND: Although genome-wide association and genomic selection studies have primarily focused on additive effects, dominance and imprinting effects play an important role in mammalian biology and development. The degree to which these non-additive genetic effects contribute to phenotypic variation and whether QTL acting in a non-additive manner can be detected in genetic association studies remain...
Topics
- Animals
- Cattle
- Genome-Wide Association Study
- Genomic Imprinting
- Genotype
- Phenotype
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci
- Reproduction
