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Article

Relationships of mitochondrial DNA mutations and select clinical diagnoses in perinatally HIV- and ART-exposed uninfected children.

Mitochondrion - 1 Nov 2024

Gojanovich Greg S, Marsit Carmen J, Kacanek Deborah, Russell Jonathan, Hudson Gavin, Van Dyke Russell B, Naini Ali B, Gerschenson Mariana

Abstract excerpt

The prevalence of pathogenic mutations within mitochondrial (mt) DNA of youth who were perinatally exposed to HIV and ART but remained uninfected (YHEU) were assessed relative to phenotypic clinical indicators of mitochondrial dysfunction (MtD). This was a cross-sectional, nested case-control study. A total of 144 cases met at least one clinical MtD definition and were matched with up to two controls each...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39218053
DOI: 10.1016/j.mito.2024.101949
PMCID: PMC11568920

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