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Effects of in utero antiretroviral exposure on mitochondrial DNA levels, mitochondrial function and oxidative stress

21 Nov 2011

Abstract excerpt

OBJECTIVES: HIV and antiretroviral (ART) exposure in utero may have deleterious effects on the infant, but uncertainty still exists. The objective of this study was to evaluate aspects of mitochondrial DNA (mtDNA) content, mitochondrial function and oxidative stress simultaneously in placenta, umbilical cord blood and infant blood in HIV/ART-exposed infants compared with uninfected controls. METHODS:...

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PMID: 22103263
DOI: 10.1111/j.1468-1293.2011.00945.x

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