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Reconstructing SARS-CoV-2 lineages from mixed wastewater sequencing data

31 Aug 2024

Abstract excerpt

Wastewater surveillance of SARS-CoV-2 has emerged as a critical tool for tracking the spread of COVID-19. In addition to estimating the relative case numbers using quantitative PCR, SARS-CoV-2 genomic RNA can be extracted from wastewater and sequenced. There are many existing techniques for using the sequenced RNA to determine the relative abundance of known lineages in a sample. However, it is very challenging...

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PMID: 39217200
DOI: 10.1038/s41598-024-70416-4

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