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Article

Clonal Hematopoiesis Is Associated With Long-Term Adverse Outcomes Following Cardiac Surgery.

Journal of the American Heart Association - 3 Sept 2024

Ninni Sandro, Vicario Rocio, Coisne Augustin, Woitrain Eloise, Tazibet Amine, Stewart Caitlin M, Diaz Luis A, White James Robert, Koussa Mohammed, Dubrulle Henri, Juthier Francis, Jungling Marie, Vincentelli André, Edme Jean-Louis, Nattel Stanley, de Winther Menno, Geissmann Frederic, Dombrowicz David, Staels Bart, Montaigne David

Abstract excerpt

BACKGROUND: Cardiac surgery triggers sterile innate immune responses leading to postoperative complications. Clonal hematopoiesis (CH) is associated with short-term inflammation-mediated outcomes after cardiac surgery. The impact of CH on long-term postoperative outcomes remains unknown. METHODS AND RESULTS: In this cohort study, patients undergoing elective cardiac surgery were included from January 2017 to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39206728
DOI: 10.1161/JAHA.123.034255
PMCID: PMC11646528

Genes

TET2
ASXL1
DNMT3A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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