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Article

Role of Vitamin D Receptor (BsmI-VDR) and Insulin Receptor (NsiI-A/G) Gene Polymorphisms in Colorectal Adenoma Susceptibility.

International journal of molecular sciences - 17 Aug 2024

Ciulei George, Orășan Olga Hilda, Cozma Angela, Negrean Vasile, Para Ioana, Ciumărnean Lorena, Leach Nicoleta, Lucaciu Roxana Liana, Hangan Adriana Corina, Procopciuc Lucia Maria

Abstract excerpt

Vitamin D deficiency and type 2 diabetes mellitus are risk factors for colorectal cancer, suggesting a role for vitamin D receptor (VDR) and insulin receptor (INSR) gene polymorphisms. We investigated the prevalence of the VDR-BsmI (rs1544410) and NsiI A/G-INSR (rs2059806) polymorphisms and their associations with colorectal adenoma (CRA) in a Romanian population. A case-control study was conducted with 110...

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Identifiers

PMID: 39201651
DOI: 10.3390/ijms25168965
PMCID: PMC11354587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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