Article
Embryonic Lethal Phenotyping to Identify Candidate Genes Related with Birth Defects.
International journal of molecular sciences - 13 Aug 2024
Yan Bing, Gong Baoming, Wang Xue, Zheng Yufang, Sun Lei, Wu Xiaohui
Abstract excerpt
Congenital birth defects contribute significantly to preterm birth, stillbirth, perinatal death, infant mortality, and adult disability. As a first step to exploring the mechanisms underlying this major clinical challenge, we analyzed the embryonic phenotypes of lethal strains generated by random mutagenesis. In this study, we report the gross embryonic and perinatal phenotypes of 55 lethal strains randomly...
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