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Pharmacological Modulation of Cognitive Test Solution in Mice of Two Genotypes.

Doklady. Biochemistry and biophysics - 1 Oct 2024

Perepelkina O V, Poletaeva I I

Abstract excerpt

Mice of two strains selected for successful solution of "object permanence" test and for lack of such solution demonstrated the differential reaction to injections of two drugs. The effects of injections of atomoxetine. which blocks the noradrenaline reuptake, and of 'non-benzodiazepine" anxiolytic afobazol was different. The success of solutions increased in mice selected for this test "non-solution": and...

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Anti-Anxiety Agents
Benzodiazepines
Cognition
Genotype
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PMID: 39196528
DOI: 10.1134/S1607672924701096

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