Article
A functional genomic framework to elucidate novel causal metabolic dysfunction-associated fatty liver disease genes.
Hepatology (Baltimore, Md.) - 1 Jul 2025
Saliba-Gustafsson Peter, Justesen Johanne M, Ranta Amanda, Sharma Disha, Bielczyk-Maczynska Ewa, Li Jiehan, Najmi Laeya A, Apodaka Maider, Aspichueta Patricia, Björck Hanna M, Eriksson Per, Schurr Theresia M, Franco-Cereceda Anders, Gloudemans Mike, Mujica Endrina, den Hoed Marcel, Assimes Themistocles L, Quertermous Thomas, Carcamo-Orive Ivan, Park Chong Y, Knowles Joshua W
Abstract excerpt
BACKGROUND AND AIMS: Metabolic dysfunction-associated fatty liver disease (MASLD) is the most prevalent chronic liver pathology in western countries, with serious public health consequences. Efforts to identify causal genes for MASLD have been hampered by the relative paucity of human data from gold standard magnetic resonance quantification of hepatic fat. To overcome insufficient sample size, genome-wide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.