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Article

Minor role of TP53 and TERT promoter mutations in medullary thyroid carcinoma: report of new cases and revision of the literature.

Endocrine - 1 Jan 2025

Casalini Roberta, Romei Cristina, Ciampi Raffaele, Ramone Teresa, Prete Alessandro, Gambale Carla, Matrone Antonio, Torregrossa Liborio, Ugolini Clara, Elisei Rossella

Abstract excerpt

PURPOSE: Aims of this study were to investigate the prevalence of TP53 and TERT mutations in Medullary Thyroid carcinoma (MTC) and their role in inducing aggressiveness in positive cases. METHODS: We performed a literature search in PubMed to identify studies investigating the prevalence of TERT and TP53 mutations in MTC. We also included data on MTC cases (n = 193) obtained at our center and unpublished. The...

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Share to Carcinoma, Neuroendocrine
Share to TERT gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to TP53 gene

Share to Mutation

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 39179735
DOI: 10.1007/s12020-024-03990-2

Genes

TP53
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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