Article
How limited molecular testing can also offer diagnostic and prognostic evaluation of thyroid nodules processed with liquid-based cytology: Role of TERT promoter and BRAF V600E mutation analysis.
Cancer cytopathology - 1 Oct 2021
Dell'Aquila Marco, Fiorentino Vincenzo, Martini Maurizio, Capodimonti Sara, Cenci Tonia, Lombardi Celestino Pio, Raffaelli Marco, Pontecorvi Alfredo, Fadda Guido, Pantanowitz Liron, Larocca Luigi Maria, Rossi Esther Diana
Abstract excerpt
BACKGROUND: Mutational analysis contributes to the diagnosis and prognosis of thyroid nodules analyzed with fine-needle aspiration cytology (FNAC). Although several advanced molecular tests based on multiple molecular markers are available for clinical use and have increased their impact on clinical management of patients, they are not widely available. Among them is BRAF V600E, one of the most studied mutations....
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