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MSH3 Homology and Potential Recombination Link to SARS-CoV-2 Furin Cleavage Site

21 Feb 2022

Abstract excerpt

Among numerous point mutation differences between the SARS-CoV-2 and the bat RaTG13 coronavirus, only the 12-nucleotide furin cleavage site (FCS) exceeds 3 nucleotides. A BLAST search revealed that a 19 nucleotide portion of the SARS.Cov2 genome encompassing the furing cleavage site is a 100% complementary match to a codon-optimized proprietary sequence that is the reverse complement of the human mutS homolog...

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Identifiers

PMID: 39176223
DOI: 10.3389/fviro.2022.834808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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