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The genetic structure of SARS‐CoV‐2 does not rule out a laboratory origin

17 Nov 2020

Abstract excerpt

Severe acute respiratory syndrome-coronavirus (SARS-CoV)-2's origin is still controversial. Genomic analyses show SARS-CoV-2 likely to be chimeric, most of its sequence closest to bat CoV RaTG13, whereas its receptor binding domain (RBD) is almost identical to that of a pangolin CoV. Chimeric viruses can arise via natural recombination or human intervention. The furin cleavage site in the spike protein of...

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PMID: 33200842
DOI: 10.1002/bies.202000240

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