Article
A roadmap to the molecular human linking multiomics with population traits and diabetes subtypes.
Nature communications - 19 Aug 2024
Halama Anna, Zaghlool Shaza, Thareja Gaurav, Kader Sara, Al Muftah Wadha, Mook-Kanamori Marjonneke, Sarwath Hina, Mohamoud Yasmin Ali, Stephan Nisha, Ameling Sabine, Pucic Baković Maja, Krumsiek Jan, Prehn Cornelia, Adamski Jerzy, Schwenk Jochen M, Friedrich Nele, Völker Uwe, Wuhrer Manfred, Lauc Gordan, Najafi-Shoushtari S Hani, Malek Joel A, Graumann Johannes, Mook-Kanamori Dennis, Schmidt Frank, Suhre Karsten
Abstract excerpt
In-depth multiomic phenotyping provides molecular insights into complex physiological processes and their pathologies. Here, we report on integrating 18 diverse deep molecular phenotyping (omics-) technologies applied to urine, blood, and saliva samples from 391 participants of the multiethnic diabetes Qatar Metabolomics Study of Diabetes (QMDiab). Using 6,304 quantitative molecular traits with 1,221,345 genetic...
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