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Article

Exploring estrogen antagonism using CRISPR/Cas9 to generate specific mutants for each of the receptors.

Chemosphere - 1 Sept 2024

Guerrero-Limón Gustavo, Muller Marc

Abstract excerpt

Endocrine disruptors are chemicals that have been in the spotlight for some time now. Their modulating action on endocrine signaling pathways made them a particularly interesting topic of research within the field of ecotoxicology. Traditionally, endocrine disrupting properties are studied using exposure to suspected chemicals. In recent years, a major breakthrough in biology has been the advent of targeted gene...

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PMID: 39159765
DOI: 10.1016/j.chemosphere.2024.143100

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