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Article

CTNNB1 exon 3 mutations in metastatic solid pseudopapillary neoplasm of the pancreas.

Journal of surgical oncology - 1 Oct 2024

Fleming Andrew M, Gehle Daniel B, Freitas Julia Pedo, Hendrick Leah E, Yakoub Danny, Abdelhafeez Hafeez, Nezakatgoo Nosratollah, Deneve Jeremiah L, Langham Max R, Glazer Evan S, Shibata David, Merchant Nipun B, Dickson Paxton V, Murphy Andrew J

Abstract excerpt

BACKGROUND AND OBJECTIVES: Solid pseudopapillary neoplasm (SPN) of the pancreas demonstrates an indolent disease course; however, some patients present with a "malignant" phenotype, including distant metastases resistant to chemotherapy. This analysis identifies molecular drivers of metastatic SPN using the world's largest clinicogenomics database. METHODS: The American Association for Cancer Research Project...

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Identifiers

PMID: 39155692
DOI: 10.1002/jso.27808

Genes

SPN
CTNNB1

Variants

Provenance

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