Article
CTNNB1 mutational analysis of solid-pseudopapillary neoplasms of the pancreas using endoscopic ultrasound-guided fine-needle aspiration and next-generation deep sequencing.
Journal of gastroenterology - 1 Feb 2015
Kubota Yoshimasa, Kawakami Hiroshi, Natsuizaka Mitsuteru, Kawakubo Kazumichi, Marukawa Katsuji, Kudo Taiki, Abe Yoko, Kubo Kimitoshi, Kuwatani Masaki, Hatanaka Yutaka, Mitsuhashi Tomoko, Matsuno Yoshihiro, Sakamoto Naoya
Abstract excerpt
BACKGROUND: Solid-pseudopapillary neoplasm (SPN), a rare neoplasm of the pancreas, frequently harbors mutations in exon 3 of the cadherin-associated protein beta 1 (CTNNB1) gene. Here, we analyzed SPN tissue for CTNNB1 mutations by deep sequencing using next-generation sequencing (NGS). METHODS:...
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